Fast, Safe, and Expressive evaluation of Google's Common Expression Language (CEL) in Python, powered by Rust. The Common Expression Language (CEL) is a non-Turing complete language designed for ...

Abstract: TPS (Tumor Proportion Score) serves as a crucial indicator to determine the eligibility of cancer patients for PD-L1 immunohistochemistry (IHC) treatment. In clinical practice, pathologists ...

Background: Immunotherapy plays a crucial role in the treatment of tumors. However, few studies have investigated the relationship between the expression of Programmed Cell Death Ligand 1 (PD-L1, ...

New research reveals PD-L1 expression enhances survival in advanced ovarian cancer, linking it to homologous recombination deficiency and treatment personalization. At the 2025 ESMO Gynecological ...

Factors Associated With Implementation of Biomarker Testing and Strategies to Improve Its Clinical Uptake in Cancer Care: Systematic Review Using Theoretical Domains Framework Observational studies or ...

This project is based on the Multiple Instance Learning (MIL) method and predicts the expression of the PD-L1 gene by analyzing H&E (hematoxylin-eosin) stained slice images in histopathology. Based on ...

A new analysis of real-world data show that just as in solid tumors, higher tumor mutational burden (TMB) and PD-L1 expression in blood cancers are linked to less-optimistic prognoses. Their ...

Nicolas Girard, MD, PhD, discusses the rationale of targeting PD-L1 and LAG-3 in NSCLC in the RELATIVITY-104 study. The phase 2 RELATIVITY-104 study (NCT04623775) aimed to evaluate the effectiveness ...

The authors provide useful data to support the existence of a regulatory pathway starting with SPI1-driven ZFP36L1 expression, that goes on to downregulate HDAC3 expression at the transcript level, ...