Scientists uncover catalytic mechanism behind fatty acid-driven plant oil production

Diacylglycerol O-acyltransferase 1 (DGAT1), the rate-limiting enzyme in triacylglycerol (TAG) biosynthesis, is a crucial ...
Northwestern's McCormick School of Engineering

How Bacteria Use Enzymes to Direct Carbon Traffic for Energy and Useful Chemicals

A new study by Professor Ludmilla Aristilde and her team shows how soil microbes steer carbon flow to adapt and create ...
EMBO Press

Inhibiting cholesterol synthesis halts rhabdomyosarcoma growth via ER stress and cell cycle ...

De novo cholesterol biosynthesis is a key metabolic vulnerability in rhabdomyosarcoma. Its inhibition halts cell ...