To study tissue samples from multiple patients, researchers use tissue microarrays (TMAs), a technology in which hundreds of tissue cores are arranged on a single glass slide for analysis by ...

In 1997, Juha Kononen, a postdoctoral fellow at the National Human Genome Research Institute, was pondering the significance of the recently developed DNA microarray. He was studying genetically ...

We used 50 archival paraffin blocks (Department of Pathology, National University Hospital, Singapore), including 15 cases of GIST with a benign outcome, 17 with a malignant outcome (13 primary ...

Emphasis on Potential Clinical Applications and Enhancing RNA Sample Quality Researchers are beginning to look at tissue microarrays (TMA) from different perspectives, including one with a strong ...

Treatment options for localized prostate cancer are many and varied, ranging from immediate radical surgery through to observation alone. Radical prostatectomy has been shown to have an overall ...

Tissue microarrays combines tens to hundreds of paraffin-embedded tissue cores into a single paraffin block. It is a practical and highly effective technique for high-throughput analyses of various ...

With respect to assay development, quality assurance and, ultimately, clinical adoption, the primary subject of this review, these advantages are critical. Implicit with these advantages, TMAs enable ...

The objective of the Tissue Resources Core is to collect, prepare and distribute high-quality human tissue samples (including solid tissues, blood and other biospecimens) to researchers located on the ...

Tissue/cell processing and embedding Tissue slide sectioning H&E staining Special stains including: PAS, ORO, Trichrome, VVG for elastin, Giemsa Sectioning of thick tissue curls or core punches for ...

Modeling bone mineral density (BMD) evolution in postmenopausal patients treated by letrozole (L), tamoxifen (T), and sequences of T and L (SAKK 21/07) No significant financial relationships to ...

Appropriate schedule of oral tegafur / uracil (UFT) in combination with irinotecan (CPT-11) and bolus 5-FU / l-leucovorin (LV) in patients (pts) with metastatic colorectal cancer (MCRC): A phase I ...