Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...
The Fanconi anaemia pathway has become a model system for researchers investigating DNA repair. The Fanconi anaemia pathway repairs DNA crosslinks that block DNA replication, and the FANCD2–FANCI ...
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