Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disorder globally, with a rising ...

The authors have proposed the Microbiota-derived metabolites–epigenetics (MDME) axis, a conceptual framework explaining how microbial metabolites function as a critical link between the environment ...

Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is the main finding of the latest research by Dr. Marcus Buschbeck and Dr.

Cancer is increasingly recognized as a systemic disease influenced by complex interactions between genetic, metabolic, immunologic, and environmental ...

Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is ...

Discover how a simple shift toward spermidine-rich foods can activate your body’s natural cellular renewal system, protecting ...

Peer-reviewed study in Cell Reports Medicine demonstrates that N17350 delivers selective, immune-activating tumor killing across solid tumor types -- N17350 targets a cancer vulnerability, via the ...

Discover how a maternal diet can influence the development of the genome, revealing the scientific basis for prenatal ...