Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers, a new study reveals.

Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is the main finding of the latest research by Dr. Marcus Buschbeck and Dr.

Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...

Chromosomal DNA is packaged with histones into nucleosomes. Following replication, sister-chromatid segregation is orchestrated to ensure that each daughter cell receives a complete set of chromosomes ...

Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re known, ...

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...