为解决 DCX 在神经元迁移中作用机制不明等问题,麦吉尔大学研究人员开展 DCX 相关研究,发现 DCX 通过调节 α -tubulin 多聚谷氨酸化限制神经突分支。该成果有助于理解相关脑部疾病,推荐科研读者阅读。 在人类大脑发育的奇妙旅程中,神经元的迁移和正确定位 ...
Figure 1: Temporal control of Dcx expression in mispositioned neurons by using Cre-dependent expression vectors and 4-OHT–activatable Cre recombinase. Figure 2: Restoration of neocortical lamination ...
Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport 1. Microtubule-associated proteins (MAPs) regulate the dynamics and ...
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