The relationship between RNA sequences and their resultant structures is central to understanding evolutionary processes and molecular robustness. Genotype–phenotype mapping studies reveal how subtle ...

Cancers are genetic diseases driven by recurrent sets of somatic mutations. Different mutations associate statistically with distinct disease risks and can therefore be useful prognostic markers. But, ...

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year’s recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher. My name is Neil Kelleher, and ...

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death. While ...

Irvine, CA - June 1, 2021 - A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the ...

Materials and Methods: APC mutations were identified in 953 FAP patients from 187 families. We used unconditional logistic regression models and a method involving generalized estimating equations to ...