为解决肺癌发生机制不明及治疗靶点匮乏的问题，研究人员开展了关于表观遗传共调节因子HCF-1通过O-GlcNAc糖基化通路调控肺癌进展的研究。研究发现HCF-1在肺癌组织中显著上调，且与OGT、O-GlcNAc及Nkx2.1水平正相关。通过基因敲降和OGT抑制剂干预，证实HCF-1-OGT轴 ...

本研究揭示了宿主细胞因子HCF-1在肝脏代谢调控中的核心作用。研究人员通过构建肝细胞特异性HCF-1敲除小鼠模型，发现HCF-1缺失会导致O-GlcNAc转移酶（OGT）蛋白稳定性下降、核定位丧失及全局O-GlcNAc糖基化水平降低，这种效应与禁食状态下的代谢响应高度相似。

Microsoft today announced that it acquired Lumenisity, a U.K.-based startup developing “hollow core fiber (HCF)” technologies primarily for data centers and ISPs. Microsoft says that the purchase, the ...

Private health insurer HCF has announced an AU$5 million (US$3.5 million) investment in XT Ventures, the nation's first venture capitalist fund for start-ups in the health, wellness, sport and fitness ...

HCF has taken a cue from the cost of living crisis, launching a new brand platform that highlights the benefits it offers as a not-for-profit health fund. Created by Clemenger BBDO, ‘We Put Our Money ...

The agreement with the not-for-profit fund comes days after Ramsay terminated its contract with Australia’s second biggest health fund, Bupa, after failing to agree on a funding increase following ...

Western Australia's largest health insurer, HBF, has pulled out of a planned merger with eastern states not-for-profit health fund HCF. The decision to withdraw from the long-mooted deal, which was ...

Western Australia's largest heath insurer, HBF, says a planned merger with a big not-for-profit health fund on the east coast of Australia will make the company one of the nation's biggest health ...

Through the creation of a new member initiative, ‘Value Ads’, via Clemenger BBDO, HCF is inviting members to take over 60 per cent of the brand’s advertising airtime and out-of-home advertising such ...