Processes yielding >500 mg plasmid DNA/L have previously been reported by Merck, Boehringer Ingelheim, and Nature Technology (NTC). Common features among these high-yield processes include the use of ...

While industrial bioprocesses have been operated in fed-batch mode for a long time, the screening of high-producer cell lines and a lot of other development work is still performed in batch mode for a ...

The US FDA’s Process Analytical Technology (PAT) initiative provides a structure for “Quality by Design” (QbD) deployment. As part this initiative, knowledge of industrial processes is gained using ...

About ATV Technologies: ATV is a leading contract development manufacturing organization specializing in advanced fermentation processes for a range of applications across the biotechnology, DSP and ...

This is a preview. Log in through your library . Abstract An automated approach to extract interpretable features of univariate or multivariate profiles (functional data) is proposed. A landmark ...

The Federal Ministry of Education and Research (BMBF) sponsors the “Smart Dosing” project for the development of intelligent disposables with 900,000 Euros. The project of the companies,m2p-labs GmbH ...