Processes yielding >500 mg plasmid DNA/L have previously been reported by Merck, Boehringer Ingelheim, and Nature Technology (NTC). Common features among these high-yield processes include the use of ...

While industrial bioprocesses have been operated in fed-batch mode for a long time, the screening of high-producer cell lines and a lot of other development work is still performed in batch mode for a ...

Pow.Bio, the pioneer in continuous biomanufacturing, Bühler Group, the global solutions provider for food, feed, and advanced ...

The US FDA’s Process Analytical Technology (PAT) initiative provides a structure for “Quality by Design” (QbD) deployment. As part this initiative, knowledge of industrial processes is gained using ...

The Federal Ministry of Education and Research (BMBF) sponsors the “Smart Dosing” project for the development of intelligent disposables with 900,000 Euros. The project of the companies,m2p-labs GmbH ...

This is a preview. Log in through your library . Abstract An automated approach to extract interpretable features of univariate or multivariate profiles (functional data) is proposed. A landmark ...