Translating knowledge of genetic disease mechanisms into gene therapies has been slow with limited clinical success. One major reason is that the transfer vectors, which are most often of viral origin ...

In the realm of gene therapy and genetic engineering, viral vectors have emerged as indispensable tools for delivering genetic material to cells. These modified viruses possess the ability to ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, No. 21 (Oct. 15, 1996), pp. 11307-11312 (6 pages) Herpes simplex virus vectors are being developed for ...

A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications. The approach, developed at Gladstone Institutes and UC ...

Viruses have been evolving for millions of years, improving their ability to transfer genetic material to the hosts they infect. When it comes to gene transfer, viruses are efficient and effective. So ...

Announcing a new article publication for Zoonoses journal. Vaccinia virus (VACV) confers cross-protective immunity against the variola virus, the causative agent of smallpox, and has therefore been ...

In a recent study posted to the bioRxiv* preprint server, researchers proposed rotavirus (RV)-based vaccine vectors with the potential for developing polyvalent vaccines targeting multiple enteric ...