The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

Although every cell in the body contains the same genetic sequence, only a subset of genes is expressed in each cell. This ...

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Gene activity has to be carefully controlled by cells so that they maintain their identity and continue to carry out their proper functions, and there are many different ways that gene expression can ...

The Tactile DNA puzzle is a tool to teach visually impaired students the chemistry and structure of DNA. The puzzle contains the 4 different nucleotides (A,T,C,G) a phosphate piece and Deoxyribose ...

Human cell division involves hundreds of proteins at its core. Knowing the 3D structure of these proteins is pivotal to understand how our genetic material is duplicated and passed through generations ...

Chip-integrated 3D nanostructured device fabricated using DNA self-assembly (Left panel). A DNA crystal is grown at a designated substrate location (about 1000 crystals on 5μm pads are shown on a ...